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Acylation Quiz

Test your knowledge on the process and mechanisms of acylation in organic chemistry. Answer the questions below to the best of your ability.

  1. What is the primary purpose of acylation in organic synthesis?

  2. Which reagent is commonly used in the acylation of alcohols to form esters?
    A. Acetic acid
    B. Acyl chloride
    C. Ethylene glycol
    D. Alcohol

  3. What is the product of the reaction between an acyl chloride and an amine?
    A. Amide
    B. Carbamate
    C. Ester
    D. Aldehyde

  4. In Friedel-Crafts acylation, which catalyst is typically employed to facilitate the reaction?
    A. Sulfuric acid
    B. Boron trifluoride
    C. Aluminium chloride
    D. Sodium hydroxide

  5. Which of the following statements about acylation is true?
    A. Acylation cannot occur with primary amines.
    B. Acylation of phenols produces ethers.
    C. Acylation creates more complex molecules by introducing an acyl group.
    D. Acylation is a non-reversible process.

  6. What type of compound results from the acylation of a phenol?
    A. Aralkyl ester
    B. Acyl phenol
    C. Ether
    D. Carboxylic acid

  7. Which of the following conditions typically favours acylation over other substitution reactions?
    A. High temperatures
    B. Presence of a haloalkane
    C. Use of a strong acid as a catalyst
    D. Low concentrations of reactants

  8. What is the mechanism of the Friedel-Crafts acylation reaction?
    Please explain the mechanism in your own words.


Make sure to review the principles of acylation, including the reagents, mechanisms, and contexts in which it is utilised. Good luck!